MEDICAL STUDIES
We did not create our products without rigorous scientific research. We hired a medical doctor to assist us in research and development of Isavera products. Below is a list of studies we referenced to help determine the material, temperature and method of action of our products. Please note that our wraps have not been a part of a medical study.
FAT FREEZING
- Selective Cryolysis: A Novel Method of Non-invasive Fat Removal
- Cryolipolysis for Noninvasive Fat Cell Destruction: Initial Results from a Pig Model
- Cryolipolysis for Reduction of Arm Fat: Safety and Efficacy of a Prototype Coolcup Applicator with Flat Contour
- A Prospective Clinical Study of Noninvasive Cryolipolysis™ for Subcutaneous Fat Layer Reduction
- Cryolipolysis Versus Laser Lipolysis on Adolescent Abdominal Adiposity
- Synergistic Effects of Cryolipolysis and Shock Waves for Noninvasive Body Contouring
- Paradoxical Adipose Hyperplasia and Cellular Effects after Cryolipolysis: A Case Report
- Clinical Efficacy of Non-invasive Cryolipolysis and Its Effects on Peripheral Nerves
- Clinical Effectiveness of Non-invasive Selective Cryolipolysis
- Multiple Same Day Cryolipolysis Treatments for the Reduction of Subcutaneous Fat Are Safe and Do Not Affect Serum Lipid Levels or Liver Function Tests
- A Cautious but Optimistic Opinion of Submental Cryolipolysisi
- Safety and Efficacy of Bilateral Submental Cryolipolysis with Quantified 3-dimensional Imaging of Fat Reduction and Skin Tightening
- Frostbite Following Cryolipolysis Treatment in a Beauty Salon: A Case Study
- Cryolipolysis for Nonsurgical Reduction of Fat in the Lateral Chest Wall Post-mastectomy
- Skin Necrosis of the Thigh after a Cryolipolysis Session: A Case Report
- Prospective Internally Controlled Blind Reviewed Clinical Evaluation of Cryolipolysis Combined with Multipolar Radiofrequency and Varipulse Technology for Enhanced Subject Results in Circumferential Fat Reduction and Skin Laxity of the Flanks
- Simulation of Cryolipolysis as a Novel Method for Noninvasive Fat Layer Reduction
- Effects of Cryolipolysis on Abdominal Adiposity
- Cryolipolysis – Scientific Background of a Current Hype in Aesthetic Medicine
- Non-invasive Tumescent Cryolipolysis Using a New 4D Handpiece: A Comparative Study with a Porcine Model
- Men at Risk for Paradoxical Adipose Hyperplasia after Cryolipolysis
- Long-term Efficacy Follow-up on Two Cryolipolysis Case Studies: 6 and 9 Years Post-treatment
- Prototype Coolcup Cryolipolysis Applicator with over 40% Reduced Treatment Time Demonstrates Equivalent Safety and Efficacy with Greater Patient Preference
- A Case of Motor Neuropathy after Cryolipolysis of the Arm
- Non-invasive Cryolipolysis to Reduce Subcutaneous Fat in the Arms
- Safety and Efficacy of Cryolipolysis for Non-invasive Reduction of Submental Fat
- Delayed Onset Pain Associated with Cryolipolysis Treatment: A Retrospective Study with Treatment Recommendations
- Male Body Contouring
- Adipose Hypertrophy Following Cryolipolysis
- Ultrasound Cavitation Versus Cryolipolysis for Non-invasive Body Contouring
- Cryolipolysis for Targeted Fat Reduction and Improved Appearance of the Enlarged Male Breast
- The Efficacy of Cryolipolysis Treatment on Arms and Inner Thighs
- Transient Alterations of Cutaneous Sensory Nerve Function by Noninvasive Cryolipolysis
- Paradoxical Adipose Hyperplasia Secondary to Cryolipolysis: An Underreported Entity?
- The Safety and Efficacy of Cryolipolysis: A Systematic Review of Available Literature
- Cryolipolysis: The Importance of Scientific Evaluation of a New Technique
- Non-invasive Subcutaneous Fat Reduction: A Review
- FDA MAUDE Data on Complications with Lasers, Light Sources, and Energy-based Devices
- Cryolipolysis for Safe and Effective Inner Thigh Fat Reduction
- Cryolipolysis Conformable-surface Applicator for Nonsurgical Fat Reduction in Lateral Thighs
- A Review of the Aesthetic Treatment of Abdominal Subcutaneous Adipose Tissue: Background, Implications, and Therapeutic Options
- Cryolipolysis and Skin Tightening
- Non-invasive Fat Reduction of the Flanks Using a New Cryolipolysis Applicator and Overlapping, Two-cycle Treatments
- Cryolipolysis in Aesthetic Plastic Surgery
- Improved Methods for Selective Cryolipolysis Results in Subcutaneous Fat Layer Reduction in a Porcine Model
- Fat Reduction in the Inner Thigh Using a Prototype Cryolipolysis Applicator
- Does Cryolipolysis Lead to Skin Tightening? A First Report of Cryodermadstringo
- An Evaluation of the Patient Population for Aesthetic Treatments Targeting Abdominal Subcutaneous Adipose Tissue
- Noninvasive Selective Cryolipolysis and Reperfusion Recovery for Localized Natural Fat Reduction and Contouring
- Three-dimensional Volumetric Quantification of Fat Loss Following Cryolipolysis
- Paradoxical Adipose Hyperplasia after Cryolipolysis
- Enhanced Clinical Outcome with Manual Massage Following Cryolipolysis Treatment: A 4-month Study of Safety and Efficacy
- Cryolipolysis: A Historical Perspective and Current Clinical Practice
- Broad Overview of a Clinical and Commercial Experience with Coolsculpting
- Longitudinal Evaluation of Cryolipolysis Efficacy: Two Case Studies
- Safety, Tolerance, and Patient Satisfaction with Noninvasive Cryolipolysis
- Non-invasive Cryolipolysis for Body Contouring in Chinese–a First Commercial Experience
- Noninvasive Body Contouring with Radiofrequency, Ultrasound, Cryolipolysis, and Low-level Laser Therapy
- Cryolipolysis for Reduction of Excess Adipose Tissue
- Cryolipolysis for Subcutaneous Fat Layer Reduction
- Non-invasive Cryolipolysis for Subcutaneous Fat Reduction Does Not Affect Serum Lipid Levels or Liver Function Tests
- Clinical Efficacy of Noninvasive Cryolipolysis and Its Effects on Peripheral Nerves
- Cryolipolysis for Fat Reduction and Body Contouring: Safety and Efficacy of Current Treatment Paradigms
- Transient Alterations of Cutaneous Sensory Nerve Function by Non-invasive Cryolipolysis
- Pre and Post Lipocryolysis Thermic Conditioning Enhances Rat Adipocyte Destruction
- Non-invasive Cryolipolysis™ for Subcutaneous Fat Reduction Does Not Affect Serum Lipid Levels or Liver Function Tests
- Selective Cryolysis: A Novel Method Of Non-invasive Fat Removal
- Broad Overview of a Clinical & Commercial Experience with Coolsculpting
- Response to “cryolipolysis: The Importance Of Scientific Evaluation of a New Technique”
- Noninvasive Body Contouring by Shock Waves And Cryolipolysis: A Clinical Study
- Clinical Efficacy of Fat Reduction on the Thigh of Korean Women Through Cryolipolysis
- Case Report Effects of Cryolipolysis on Abdominal Adiposity
COLD THERMOGENESIS
- Cold exposure increases adiponectin levels
- Adiponectin burns fat
- Cold exposure increases powerful anti-oxidant glutathione
- Adiponectin, obesity, insulin resistance, and fat-burning
- Adiponectin resistance in obesity
- Intermittent fasting likely produces new BAT
- BAT and food digestion
- Women and BAT levels
- Capsinoids increases BAT activity
- Sleep, light-cycles, melatonin and BAT in humans
- Cold exposure, blood glucose, and BAT in rats
- Glucose utilization, BAT, and intermittent fasting in rats
- Carb and fat burning ratios vary during shivering
- Cold exposure and longevity in mice
- Cold exposure boosts the immune system
- Low adiponectin related to inflammatory heart disease
- BAT burns glucose and boosts metabolism in humans
- BAT therapy to combat obesity
- BAT burns fat in the blood stream
- BAT, glucose, insulin, and cold stimulus
- BAT activity in humans inversely correlate to obesity
- BAT-disabled mice become obese
- Rising environmental temperatures linked to obesity?
- Brown Fat (BAT) detected in subjects after cold exposure
- Age, gender, insulin sensitivity, and other factors in BAT activity
- Exercise in humans and mice can create new BAT (backup)
- BAT in various age groups
- Exercise increases adiponectin levels in obese men
- Cold therapy, but not ephedrine, activate BAT
- BAT, thermogenesis, and bone density
- The sympathetic nervous system and fat-burning during cold exposure
- Skeletal muscle uncoupling after thermal loading
- Adiponectin as a treatment for obesity and heart disease
- Adiponectin, fasting, and circadian rhythms